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When the bacterium continuously grows to high cell density, the AHLs accumulate to high concentration.
This antibody-expressing IAV grows to high titers, and the antibodies secreted from infected cells exhibit comparable functionality with hybridoma-produced antibodies.
Currently, for influenza A, these strains are produced by a double infection of embryonated hens' eggs using the recommended strain and the laboratory strain PR8 which grows to high titre in eggs, in order to produce a high growth reassortant (HGR).
This system provides an attractive solution to the production of internal controls for rRT-PCR assays since CPMV grows to high yields in plants, the particles are thermostable, RNase resistant and simple purification of RNA-2 containing capsids yields a preparation which is non-infectious.
For the second parameter combination (slow 2), the tumor cell population escapes control and grows to high levels.
Subsequently, as the drug sensitive population of bacteria dwindles, the mutant population grows to high burden allowing the occurrence of mutations to a second drug; ensuing exposure to that drug now selects for doubly resistant bacilli.
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Importantly, Ad35 can be grown to high titers with a low particle-to-PFU ratio.
Both recombinant viruses expressed the inserted HA stably and grew to high titers.
Our results showed that all the tested H5N1 vaccine viruses grew to high titers in eggs.
All three cell lines attached well to the scaffolds and grew to high densities as observed with scanning electron microscopy.
In bioreactor, the engineered P. pastoris was grown to high cell densities and produced a four-fold increase in SAM accumulation than cultivation in the shake flask.
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