There is a growing methodological literature on mixed method research [17], [18], [19], [20], and even a dedicated Journal of Mixed Methods Research.
The research community is fortunate to have a growing methodological armory with which to fight these battles, including technological advances such as next-generation sequencing (Williams et al., 2009), alongside an ever-expanding experimental toolkit for functionally dissecting brain circuitry (Arenkiel & Ehlers, 2009).
IWRM, it is argued, has to contend with a growing plethora of methodological and motivational questions.
A growing body of methodological research sheds light on the validity and reliability of social network survey data regarding a single relation, but much less attention has been paid to the measurement of multiplex networks and the validity of comparisons among criterion relations.
There is a growing literature addressing methodological issues such as DNA pool construction, genotyping assays, and statistical analysis [ 9- 12], and the strengths and weaknesses of DNA pooling have recently been reviewed [ 13].
Djellal [12] discusses the distinction between services dealing with information and "non-informational" services and demonstrates, in particular for road haulage services, the co-existence of material configurations with a growing integration of information, methodological and relational aspects.
Preoperative Δ VT2T1 value, a preoperative estimation of the difference between tumor volumes on T2-weighted MRI images and on postcontrast T1-weighted MRI images, was also assessed to define the tumor growing pattern, following the methodological procedure described by Skrap et al. [ 8].
Although there is growing consensus on the main methodological issues, there remain many uncertainties when performing an external cost assessment in practice.
For these reasons, the concept of human subjects research policy and regulation informs this entry, along with disciplinary standards, which will explore the growing areas of ethical and methodological complexity, including personal identifiability, reputational risk and harm, notions of public space and public text, ownership, and longevity of data as they relate to Internet research.
As a consequence of ongoing methodological advancement, a growing number of new oncogenes and tumor suppressors have been identified [9].
Based on methodological arguments, a growing interest in PROs emerged, culminating in a spontaneous proposal at the final session to invite patients to the next conference.
