Cas arrays could be further grouped into six subtypes, of which five occurred in all three species and one (I-U_Sa) was only observed in S. arenicola.
Although 39 of the isolates had identical PFGE patterns (PFGE type I), the remaining 30 isolates were grouped into five subtypes: Ia (2 isolates), Ib (10 isolates), Ic (1 isolate), Id (2 isolates and Ie (15 isolates).
Based on gene expression data, Shah et al. recently suggested that gastric carcinomas be grouped into three different subtypes [ 16].
These subtypes vary in tumor gene expression and phenotype, and are most commonly grouped into four major subtypes: luminal A, luminal B, HER2-overexpressing and triple negative (or basal-like).
The application of the panel allowed cases to be grouped into five molecular subtypes according to an algorithm by Sassi et al. [ 9] modified as follows: Luminal-A: ER+ and/or PR+, c-erbB-2–, regardless of CK5/6, CK14, p63 staining.
A subsequent study extended this by dividing the luminal/ER-positive group into three subtypes: luminal A, B, and C (Sorlie et al, 2001), but existence of the luminal C group remains uncertain (Sorlie et al, 2003).
Sørlie et al. (2001) retained the basal-like, Erb-B2+ (re-named ERBB2+ in Sørlie et al. (2001)), and normal-breast-like groups but divided the luminal epithelial/ER+ group into three subtypes: luminal A, luminal B, and luminal C. Centroids corresponding to each of these six groups were made on one dataset and used to classify the samples of another dataset.
The varied Bulgarian natural environment has produced about 20 soil types and subtypes, which may be grouped into three main regions.
SOMAmers were grouped into three unique mixes.
The original study used unsupervised hierarchical clustering to group patients into three subtypes of DLBCL: germinal center-like (GC), activated B cell-like (AB), and type III.
