A univariate sub-group survival analysis according to FIGO stages showed that LND was associated with overall survival in patients with FIGO stage I (P=0.01), but not with stage II (P=0.7), III (P=0.8), and IV (P=0.3).
The median number of CD4+, FoxP3+ and CD8+ TILs was 16.7, 2.1 and 3.4 per high-power field, respectively in the 90 grade IV GBM tissues, which was used as the cutoff point to define a high infiltration group and a low infiltration group for survival analysis.
However, ET-levels did not change in group 3. Survival analysis was explored for these three groups.
a 1 on POD 19 for septic shock (Excluded from Laparoscopic group for survival analysis).
b 1on POD#1 for cardiac arrest (Excluded from Laparoscopic group for survival analysis).
Patients with microscopically positive resection margins, an R1 resection (defined as cases with presence of microscopic tumor cells within 1 mm of the proximal or distal surgical resection margins), were used as a control group for survival analysis.
Since qPCR results showed that XIAP/XAF1 ratio strongly correlated with prognosis, we divided patients in four groups for survival analysis, depending on the following immunoreactivity patterns: group 1, XIAP low and XAF1 negative; group 2, XIAP low and XAF1 positive; group 3, XIAP high and XAF1 negative and group 4, XIAP high and XAF1 positive.
For both groups in survival analysis, n = 11.
In the intent-to-treat analysis, LOS was compared for the two study groups using survival analysis: the Kaplan-Meier estimator and the log-rank test.
Differences between risk groups in survival analysis were also significant for both 17-gene (P = 0.023) and eight-gene (P = 0.004, Figure 5C) models.
