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R 0) resections were achieved in 16 patients, while R(1) resections were achieved in 10, and margins were grossly positive in 3 patients.
Of 145 patients evaluated, 42 were considered to have resectable tumors by CT criteria, and 37 (88%) underwent potentially curative pancreaticoduodenectomy. Six patients were found to have a microscopically positive retroperitoneal resection margin; no patient had a grossly positive resection margin.
Specimen margins were categorized as clear, microscopically positive, or grossly positive.
Even when grossly positive nodes were found, complete node dissection was performed in those areas.
Fifty patients had negative resection margins, 32 had microscopically positive margins, and 12 had grossly positive margins.
A more extensive surgical approach including pelvic lymphadenectomy should be reserved for the debulking of grossly positive nodes.
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In sharp contrast, Sall3−/− ; Gad1-EGFP mice showed very weak expression of NF165 in the OPL (Fig. 10D); the few correctly positioned GFP-positive cell bodies extended grossly atrophic NF165-positive dendritic processes (Fig. 10D, asterisks).
Thus, of the 52 patients who had surgery, the resection was complete for 46, grossly complete for five (positive margin on paraffin section), and unresectable for one.
The duration of tuberculosis from onset to cure or death is approximately 3 years and appears to be grossly similar for smear-positive and smear-negative tuberculosis.
Furthermore, the literature contains numerous case reports, case series, letters to the editors, and grossly underpowered studies demonstrating significant positive results, yet few high-quality randomized controlled trials.
Digital photographs of crypts were taken at high (400 600X) magnification (Zeiss AxioHOME microscope) and crypt epithelial cells (paneth and non-paneth) intestinal sections were examined using ImageJ software and classified as BrdU positive if they grossly demonstrated brown-stained nuclei from DAB staining or as BrdU negative if they were blue stained nuclei.
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