Sentence examples for grossly affecting from inspiring English sources

They don't know how to build it and they're not realizing how this is grossly affecting their revenue and financial net worth.

We reported that the overexpression of IRP1 (either wild type, or a mutant carrying a C437S substitution that has constitutive IRE-binding activity) drastically inhibits the growth of tumor xenografts, without grossly affecting their iron content [19].

The main motivation directing the development of PIR was to establish a method enabling the assessment of proteasomal inhibition in a cellular context, based on the unequivocal translocation of a fluorescent reporter protein from the cytoplasm to the nucleus upon proteasomal inhibition, without grossly affecting its overall levels.

The forced re-expression of SSeCKS could suppress v-Src-induced oncogenic growth in vitro without grossly affecting the ability of v-Src to phosphorylate cellular substrates [ 6].

We recommend that maintenance Orgaran® infusion rates ≥400 U/hour should be avoided unless serious circuit clotting is grossly affecting the haemofilter life.

Our findings show that an excess of SKAP-EB interaction can result in an anaphase onset delay, without grossly affecting other microtubule-mediated functions such as bipolar assembly or chromosome congression.

This would grossly affect the gas quantification accuracy of such electronic nose (E-nose) instruments.

Exposure to O3 did not grossly affect neurobehavioral development, whereas it consistently impaired reversal learning in the Morris water maze test in both prenatally and adult exposed mice.

He also noted one of the primary distinctions between magnetism and electricity: the force between magnetic objects tends to align the objects relative to each other and is affected only slightly by most intervening objects, while the force between electrified objects is primarily a force of attraction or repulsion between the objects and is grossly affected by intervening matter.

The judge said the defence had not proved its case: "The evidence led by the defendant of the plaintiff's consumption of alcohol fell well short of proof of a loss of control over physical or mental powers in the context of a disposition or tendency to be habitually so grossly affected".

Interestingly, activity in motor spinal cord regions and corresponding twitches and complex movements were not grossly affected by deafferentation, which is in keeping with previous behavioural results, where no effect of deafferentation on the expression and structure of twitches was shown7.