Sentence examples similar to gross cell death from inspiring English sources
Histological and TdT-mediated 2′-deoxyuridine, 5′-triphosphate (dUTP) nick end labelling (assay) (TUNEL) examination of the brain, heart, lungs, small intestine, kidney, liver and spleen from clofazimine treated animals revealed no gross abnormalities and cell death in these organs with respect to untreated ones (Fig 8D and E).
From a cellular perspective, risking the introduction of point mutations during translesion synthesis may be preferable to resorting to more drastic mechanisms of DNA repair, which may cause gross chromosomal aberrations or cell death.
We investigated whether failure of ICL repair contributes to prolongation of G2 arrest, gross chromosomal abnormalities, and cell death.
Mutations that affect the ability of BRCA2 to interact with RAD51, or cause defects in the relocalization of the BRCA2/RAD51 complex, would be expected to have severe effects on the normal efficiency of homologous recombination, potentially leading to gross chromosomal rearrangements and cell death.
A major feature of apoptotic cell death is gross structural changes, one of which is the loss of cell cell contacts.
These findings suggest that hTRM9L is not inducing gross changes in apoptotic or autophagic cell death that would account for the growth inhibitory function.
It suggests that the gross developmental abnormalities observed in hif2α morphants is possibly caused by extensive cell death occurred in the early stage of development.
Cell Death Differ 2017 Feb 24.
