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Given this grievous outcome, novel, effective treatments are urgently needed for this disease.
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It all boils down to one grievous issue.
Transmission congestion management became a grievous issue with the increase of competitiveness in the power systems.
He had tried desperately to carry on and when he finally accepted it was futile it felt like a grievous setback to Portugal's hopes of denying France the outcome that would have meant so much in this city.
None involved grievous violence.
This a grievous blow.
Some of them grievous.
The news is grievous.
And the grievous sore?
"Such misconduct does grievous harm to investors".
This is a grievous, self-inflicted wound.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com