Sentence examples for greatly sensitized from inspiring English sources

The data presented here clearly show that the hypogravity environment greatly sensitized the CD133 cells to various chemotherapeutic agents.

Interestingly, we also found that the hypogravity environment of the HFB greatly sensitized the CD133 cancer cells, which are normally resistant to chemo treatment, to become susceptible to various chemotherapeutic agents, paving the way to less toxic and more effective chemotherapeutic treatment in patients.

MX greatly sensitized UDG+/+ cells to pemetrexed and reduced the pemetrexed IC50 value from 220 to 80 nM.

Instead, we were surprised to find that A20 depletion had an opposite effect and greatly sensitized the cells to death.

In line with this, pharmacologic inhibition of COX-2 by celecoxib greatly sensitized the PDAC cell lines in an extent similar to c-Rel or NFATc2 inhibition.

It is well documented that cells lacking HR function are greatly sensitized to a panel of DNA damaging agents, including MMC [26].

In accord with this observation, PHD1 knockdown greatly sensitizes CRC to 5-FU in mice.

Smac mimetics trigger auto-ubiquitination and degradation of cellular IAPs and can greatly sensitize cancer cells to apoptosis or necroptosis.

Moreover, knockdown of BRCA2 greatly sensitizes glioma cells to DNA double strand breaks and the induction of cell death following temozolomide and nimustine treament [ 29].

It is possible that, although small changes in Lck activity greatly sensitize the TCR to weak agonists, such small changes do not as effectively engage negative feedback mechanisms.

Here, we demonstrated that PPD greatly sensitizes K562 and HT29 cells to doxorubicin to similar extent where Cisplatin does in additive or synergistic ways, depending on different combinations of their concentrations.