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Droplet sample introduction for MS allows fast analysis and greatly reduced sample consumption, suggesting potential for HTS.
We also divided the data set into observations with high versus low traffic counts and refitted the AR models, albeit with a greatly reduced sample size.
Furthermore, though our data come from characterization of a complex Arabidopsis protein digest, all spectra were collected during an extended LC-MALDI separation that greatly reduced sample complexity in any single spectrum.
First, we had a greatly reduced sample size in GPS data because of the noncompliance of the subjects and subjects dropping out of the GPS tracking with the advancement in pregnancy.
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They demonstrated by simulation that this greatly reduced sampling and mean square errors, and, moreover, that this held for animal model analyses with a complicated pedigree structure and many different types of covariances between relatives.
The large-scale procedure greatly reduces sample processing effort but does increase the cost of analysis.
We present a method of targeted ancient DNA sequence retrieval that greatly reduces sample destruction and sequencing demands and use this method to reconstruct the complete mitochondrial DNA (mtDNA) genomes of five Neandertals from across their geographic range.
Recently, automated brain mapping methods, such as tensor-based morphometry (TBM) of structural MRI, have outperformed cognitive measures in their precision and power to track disease progression, greatly reducing sample size estimates for drug trials.
Highly hydrophobic hexane simplifies the tissue homogenate extraction procedure and greatly reduces sample complexity without sacrificing overall analytical performance.
The proposed seamless phase II/III TB trial designs are shown to greatly reduce sample size requirements and trial duration compared to conducting separate phase II and III trials.
Analysis of 96 samples in parallel greatly reduces sample-to-sample variation and can be completed in one day.
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