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I expect that an important incentive for such greatly needed studies will be the availability of new methods for in vivo observations, methods that allow visualization of proteins in their natural environment and study of their movements and interactions in situ.
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It also provides the results of one of the few - though greatly needed - replication studies in epigenetic epidemiology.
As pointed out recently in an editorial from the American Journal of Psychiatry [ 88], this type of research is greatly needed in a field in which most imaging studies have been conducted in adults.
The greater number of dogs who are diagnosed yearly with osteosarcoma, along with the more accelerated progression to metastasis compared to pediatric osteosarcoma, provides a greatly needed resource for the study of this rare pediatric cancer and may be necessary for optimal progress to be made.
In the case of diabetes, databases on body composition, strength, and function in large clinical series of patients are greatly needed and might be feasible ancillary studies to the many existing multicenter observational and intervention programs.
Indeed, noninvasive and reliable biomarkers detectable in IS, suitable to outline a quick disease readout, are greatly needed to speed up proof-of-concept studies in patients with COPD.
Thus, further studies in this area are greatly needed in order to clarify the phenotypes associated with specific VEGF-A SNPs in prostate cancer patients.
Due to the excessive OOGP decommissioning in the next decade and many possible options can be used to decommission OOGPs, studying potential decommissioning options is greatly needed.
Although difficult to perform because of the rarity of EPN, randomized controlled studies for management of EPN are greatly needed.
Studies of toga biogenesis are also greatly needed, both to test that it really is a highly modified negibacterial OM and to understand how and why that modification occurred.
Thus, new algorithms that can accurately detect and quantify filopodia in non-neural cells are greatly needed, as this will allow more rigorous and thorough study of the relationships between filopodia characteristics and the factors that control them.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com