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It has also greatly increased sensitivity in the diagnosis of acute cerebral ischaemia.
Unfortunately near-threshold operation is plagued by greatly increased sensitivity to threshold voltage variations, such as those caused by ambient temperature fluctuation.
The deletion males on the HF diet had lower resting glucose levels and a smaller peak after glucose injection (Fig. 5B), as well as a greatly increased sensitivity to insulin (Fig. 5D).
Of potential therapeutic importance, we have demonstrated that cancer cells with aberrant β-catenin activity exhibit greatly increased sensitivity to CK1ε inhibition, mediated either by RNAi or by use of small molecule inhibitors of CK1ε (Figs. 2, 3).
However, reconstitution of p65 greatly increased sensitivity to induction of apoptosis by these agents.
They were more active than normal mice and had more body fat, and showed greatly increased sensitivity to insulin.
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A single TNT molecule can quench many thousands of fluorescence reactions, greatly increasing sensitivity.
As a monitoring alternative, DNA-based methods would greatly increase sensitivity and speed of detection of resistance alleles, but their development is dependent on the identification of resistance alleles.
The presence of GAGs at CHO cell surface greatly increases sensitivity to low concentrations of ATP and changes the main P2X7 kinetic parameters EC50, Hill coefficient and Emax.
However, such colorimetric assays are relatively insensitive and, as has been pointed out previously for βgal, chemiluminescent substrates can greatly increase sensitivity [ 3].
We found that lowering the cutpoint to 2 ng/ml, while greatly increasing sensitivity, led to an 80% false positive rate.
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