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Thus the F508delCFTR fragmentation fingerprint manifests as a ladder pattern and also displays a greatly fragmented cognate NBD2 (also see the immunoprecipitation data in Figure 3, lanes 3 and 6).
During the past century, the tiger population has declined sharply from more than 3000 to fewer than 600 individuals, and its habitat has become much smaller and greatly fragmented.
This inherent diversity leads to a greatly fragmented domain from the perspectives of both underlying theory and design methodology.
Landholding patterns in the West were not uniform; some areas had greatly fragmented landholding patterns, but in other areas large contiguous blocks of land were the norm.
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As a result, tiger subpopulations also became significantly more fragmented, greatly increasing their threat of extinction in each individual forest and as a species.
We live in an age of fragmentation: fragmented communities, fragmented lives, fragmented attention.
In the past, mobile video apps tied to live events suffered greatly, with frozen screens, fragmented video and audio static.
The problem is that even with a willing public and a fresh slate, the two main parties — the People of Freedom and the fragmented Democratic Party — greatly distrust each other, and yet are not strong enough to win alone.
This is a highly fragmented market, greatly in need of an organized marketplace, but unfortunately others have realized this and have already made great strides to enter.
Our observations that the MRH2 mutation causes cortical MT to be randomly oriented and fragmented and greatly enhances the CA-rop2-activated disruption of MT organization (Figure 4) suggest that MRH2 is important for stabilizing MT or maintaining MT orientation.
Thus land clearing must have further fragmented an already fragmented population, as well as greatly reduced the number of individual plants.
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