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Steroid hormones clearly play a large role in breast cancer etiology, and identification of risk associated with genetic differences in their biosynthesis and metabolism could greatly elucidate mechanistic pathways and make inroads towards prevention for public health.
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The Calladine construction greatly elucidates behaviour.
The underlying reasons for this disappointingly low survival rate remains to be greatly elucidated.
The genetic control of longevity has been greatly elucidated in model organisms.
For example, although miRNA does not appear to add prognostic power to multidimensional genomic models in GBM (Zhao et al, 2014), the involvement of miRNAs in GBM is evident and has been greatly elucidated due to TCGA.
Structural work has greatly elucidated the features important for substrate interactions, with a peroxide-bound complex of Aeropyrum pernix thiol peroxidase providing a view of a true Prx Michaelis complex.
A similar classification would greatly help elucidate the role of cutaneous HPV types in SCCC and skin carcinoma.
Over the last decade, systems biology has contributed greatly towards elucidating the underlying mechanisms associated with various infectious diseases [ 114, 115].
All of these models greatly helped to elucidate the roles of different genes in prostate carcinogenesis and tumor progression.
Better understanding of the genetic and epigenetic changes and their interactions at all the stages during HCC progression will greatly facilitate to elucidate the pathogenesis of HCC.
The development of in vitro models of epithelial-mesenchymal interaction may greatly contribute to elucidate the effects mediated by the stromal fibroblasts on the epithelial cells and the molecular mechanisms involved in the CHO pathogenesis.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com