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In particular, we searched for alleles with little or no divergence between D. simulans and D. sechellia that greatly diverged from D. melanogaster.
We also showed that our model could be used towards identifying orthologous hits in greatly diverged sequences.
Probably due to the above different substitutional patterns, the evolution of the orthologous genes has greatly diverged at the boundary of invertebrates and vertebrates.
A CRM can be isolated without prior knowledge of its regulators or which genes are co-expressed with its target genes, such as those CRMs identified by deep conservation with greatly diverged species [26] [28].
Remarkably, according to the transcriptional program of mouse hepatocytes carrying human chromosome 21, Wilson et al. [38] have recently unraveled that the regulatory sequences between human and mouse have greatly diverged.
Usually, duplicated SNAREs are not very greatly diverged in fungi.
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This path leads, in the various religions, into greatly diverging directions.
Even though they are both very densely packed with genes, they greatly diverge at the levels of their overall structure, gene content and gene order (Table 1).
These approaches may involve manually examining regions where read matches greatly diverge from the reference [ 15], post-processing the output of SV-prediction tools that examine SRA and PEM evidence [ 16], or comparing the output of de novo assembly tools to the reference genome [ 17, 18].
44 Variants have been described with either tyrosine or serine at position 116 that greatly diverge in their interaction (either strong or weak, respectively) with other proteins in the endoplasmic reticulum for antigen presentation at the cell surface.
Based on gene sequence analysis, CheA75a in D. simulans has diverged greatly from those in the other two species (∼68% divergence in peptide sequence between D. simulans and the two other species).
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