The phrase "greatly challenge" is correct and usable in written English.
It can be used when describing a significant or intense difficulty or obstacle that someone or something presents.
Example: "The new regulations will greatly challenge our current business model and require us to adapt quickly."
Alternatives: "significantly challenge" or "profoundly challenge".
The growing popularity of massively accessed Web applications that store and analyze large amounts of data, being Facebook, Twitter and Google Search some prominent examples of such applications, have posed new requirements that greatly challenge traditional RDBMS.
Besides, integration of multi datasets from various sequencing strategies are exploited to tackle the complex genome assembly [29], which greatly challenge the development of assembly algorithms to suit for diverse short reads.
Ever since the use of Oct4, Sox2, Klf4 and c-Myc (OSKM) to reprogram somatic cells into pluripotent stem cells, breakthroughs in the iPSC field have been reported frequently and these advances greatly challenge our conventional understanding of cell fate determination.
Contact: [email protected] Supplementary information: Supplementary data are available at Bioinformatics online In recent years, the data volumes generated by next-generation sequencing (NGS) technologies have been growing at a pace that has now begun to greatly challenge the data processing and storage capacities of modern compute systems (Medini et al., 2008).
"Even if simply clearing vacant lots were the solution, Detroit would be greatly challenged.
While the information is useful in many aspects, personal privacy is greatly challenged too.
The ratcheting effect greatly challenges the design of components of the nuclear power plant.
Moreover, there is considerable sampling uncertainty affecting the univariate and bivariate hydrologic risk evaluation, which greatly challenges measures of future flood mitigation.
The large credible interval of drought severity and duration greatly challenges measures of mitigation of drought hazards and water resource management.
Use of nuclear energy as a heating source is greatly challenged by the economic factor since the nuclear heating reactors have relative small size and often the lower plant load factor.
To address the dramatic voltage fluctuations and wind turbine generators (WTGs) cascading trip faults, which have been greatly challenged the wind pool area's operation, a hierarchical automatic voltage control system to support wind power integration (Wind-AVC) is designed and presented in this paper.
