Sentence examples for greatest problem in the from inspiring English sources

It's funny--it's the greatest problem in the world to have.

Perhaps the greatest problem in the candidate gene era of COPD genetic studies was improper candidate gene selection, which reflects our limited understanding of COPD pathogenesis.

Traditionally, the greatest problem in this notorious "problem play" is the relationship of its romantic leads, Helena (Annie Parisse), the wistful but enterprising doctor's daughter, and Bertram (Andre Holland), the arrogant young aristocrat whom she adores.

"I think that the greatest problem in this hospital is that they [the administrators] do not comprehend that this is something we do almost every week with patients and relatives".

But the county monitoring has also included testing at vineyards and golf courses and has found by far the greatest problems in the farm areas.

Vaccine availability varies from year to year because it must be made anew each summer and fall to protect against the viral strains likely to cause the greatest problems in the coming winter.

One of the greatest problems in the treatment of attitudes is the issue of logical omniscience: humans are cognitively limited agents, and are not aware of all the consequences of their beliefs and desires.

During this year 2005, drought has become one of the greatest problems in the Spanish Southeast and even some cities have suffered water restrictions trying to solve, at least partially, the unexpected situation of last summer.

A study in the French-speaking part of Switzerland identified poorly planned discharges as one of the greatest problems in the treatment of persons with mental disorders [ 3].

Arguably, the two greatest problems in the management of chemical insecticides are the evolution of resistance in the target pests and the off-target toxicities caused by residues of the pesticides that have dispersed away from their point of application.

One of the greatest problems in the development and validation of biomarkers is the ambiguity of the term and the failure to recognize that biomarker validity means fitness for intended use.