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In this analysis, LPS stimulation of DC induced the greatest gene expression changes in principle component (PC 1 and PC2.
We therefore used principle component analysis (PCA) of transcriptional profiles to compare components of the data that are responsible for the greatest gene expression differences (Figure 6B).
The next set of functional groups displaying the greatest gene expression changes in relation to EHEC O157∶H7 growth conditions were those encoding macromolecule biosynthesis (amino acid biosynthesis: 3.5%; biosynthesis of cofactors: 0.8%; carbon compound biosynthesis: 3.1%), cell structure components (3.8%), regulatory components (0.8%), and putative factors (0.8 11.5%).
In A. thaliana the greatest gene expression in response to Pst DC3000 occurs 12 hpi and involves approximately 2700 genes over all time points [ 30, 31].
TST data were subjected to PCA and quantitative differences in each gene signature were represented by the PC1 scores, which reflect the greatest gene expression differences between samples.
We believed that by analyzing the viromes in each of these subjects, we would find that the most abundant viruses in each subject also would have the greatest gene expression.
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Increasing the lysine and histidine residues reduced particle size and increased zeta potential of DNA complexes, leading to greater gene expression efficiency.
There are limits to the improvement in adaptation when sexual selection is strong and favours greater gene expression in males (the heterogametic sex).
Particularly, the largest QD bundled NPs examined, QD655, had a much higher uptake capability and greater gene expression ability than the other QD NPs (QD525, QD565, and QD605).
VX2 tumors infected with Ad-CMV-HA-SSTR2 upon intra-arterial delivery with AII had greater in vivo biodistribution, thus greater gene expression, than those without AII (p < 0.01, n = 6).
Similarly, VX2 tumors infected with Ad-CMV-HA-SSTR2 upon IA delivery with AII had greater biodistribution, thus greater gene expression, than those with the negative control Ad-CMV-GFP (p < 0.01).
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