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Discover Ludwig"greatest effect" is correct and usable in written English.
You can use it when referring to the most significant outcome or result of an action or phenomenon. For example, "The proposed policy has had the greatest effect on the economy."
Exact(60)
Full brass power is saved for moments of greatest effect.
His views, however, had the greatest effect on later reformers.
The (O/Na) molar ratio had the greatest effect.
The amount of KOH had the greatest effect.
Perhaps the greatest effect from climate change on global fisheries could be through plankton.
The NHS needs to direct these resources to where they will have the greatest effect.
What do you feel has been the greatest effect of your investigation?
This factor will have by far the greatest effect in reducing demand than any other.
They also seem to highlight the pianist's sensibilities to greatest effect.
Why not make the case with more consistency instead of seeking greatest effect?
What kind of physical activity has the greatest effect, we don't really know".
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com