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In each case, EGCG and HNK bound with the greatest affinity to the NBD as judged by the relative changes in the melting temperature (Tm) of the NBD and SBD domains.
Grand Terre, our oil-impacted site, is located near the center of the species' range (site 4 on Figure 1), and fish from this site have greatest affinity to the western phylogeographic cluster of populations.
Globally, the biological role of CRP after binding to ligands is to trigger the complement pathway [ 7] CRP binds with greatest affinity to phosphocholine residues, and with less affinity to native and modified lipoproteins [ 44], damaged cell membranes, a number of phospholipids, small nuclear ribonucleoprotein particles, and apoptotic cells [ 45].
Together with a competition mechanism, the map then organizes itself so that the RGC with highest affinity for the location with highest affinity innervates it, leaving the RGC with the next greatest affinity to innervate the SC neuron with the next greatest affinity, and so on.
AF-69 and AF-78 both have R2 extensions that violate the envelope at P1/P1′, and both inhibitors lose their greatest affinity to the M1 variant with characteristic mutations G48V and V82A, which are close to the envelope at P1/P1′, consistent with the notion that the inhibitors violate the envelope to make non-substrate-like P1/P1′ interactions that are disturbed in the M1 variant.
Similar(55)
However, unlike the Kyrgyz, the populations with the greatest affinities to Altaian Kazakh populations were Mongolians.
"We feel greater affinity to those who are Jewish".
There is no great affinity to United to draw Bale in anyway.
Sunitinib and Doxorubicin possess great affinity to inhibit these cancers causing protein.
Some 30 complete skeletons and 200 partial skeletons of the creature which had greater affinity to a modern-day zebra than to a horse have been excavated.
As such, FRBROO manifests a great affinity to the LexML domain ("A Time-aware Ontology for Legal Resources," João Lima et al., Proceedings of the Tenth International ISKO Conference, 2008).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com