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Unlike fluorogenic peptide substrates, use of ubiquitinated protein substrates not only confer greater stringency in terms of proteasomal hydrolysis, but also involve the participation of the19S regulatory component.
Metabolic phenotypes have been shown to be better predicted than in vitro residual activities, probably because of greater stringency in the phenotyping process.
Spencer's "liberal" utilitarianism, however, differs from Mill's in several respects, including principally the greater stringency that Spencer ascribed to moral rights.
"(Turnbull should) look seriously at instituting a moratorium on immigration of Muslims to Australia or, at the very least, greater stringency in vetting those wishing to come to our country," she said.
We observed that a shift to the right indicates greater stringency as the minimum level of transcript needed to sustain 50% cell viability increases.
For greater stringency, we chose to employ a single high dose challenge of animals pretreated with DepoProvera, conditions which increase susceptibility to infection.
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Multiple regression suggested that greater examiner stringency was associated with greater examiner experience and being from an ethnic minority.
An analysis of the construction of each contig revealed the merging of previous smaller contigs during the final steps of the autobuild process at greater cutoffs/lower stringency (1e-20 and 1e-15), which explains the presence of incompatible markers in these contigs.
In 2003 Lawson analyzed 8 OSCEs administered in 2002 by the Canadian Chiropractic Examining board; this revealed that the variability due to examiner stringency was greater than the variability due to candidates [ 12].
Using a 10-fold or greater upregulation or downregulation stringency for the EMT array, we identified upregulation of Cdh2, Igfbp4, and Tspan13, as well as downregulation of Col1α2, Bmp7, Wnt11, Gng11, Vcan, Tmeff1, and Dsc2 in TβRII KO epithelia compared with TβRIIfl/fl epithelia.
For instance, sequence 1 can be linked to sequence 2, itself linked to sequence 3, while sequences 1 and 3 are not directly connected because they do not share a greater similarity than the stringency threshold used to construct the network.
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