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Direct democracy doesn't work when, as James Madison explained, "the greater number of citizens and greater sphere of country" won't let it.
Madison distinguished between these two forms of government as follows: "The two great points of difference between a democracy and a republic are: first, the delegation of the government, in the latter, to a small number of citizens elected by the rest; secondly, the greater number of citizens, and greater sphere of country, over which the latter may be extended".
The two great points of difference between a Democracy and a Republic are, first, the delegation of the Government, in the latter, to a small number of citizens elected by the rest: secondly, the greater number of citizens, and greater sphere of country, over which the latter may be extended.
The minority CD44+CD24low+ population shows greater sphere formation and gives rise to CD44+CD24neg progeny.
Effective management of modern chronic disease thus needs to be broadened to encompass a greater sphere of influence than is often publically perceived or politically popular.
Findings to date had revealed that CD44+CD24low+ show greater sphere forming ability, more frequent tumour initiating cells (DT-22), and are driven by N1-ICD.
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In our work, we used CD44/CD166 double staining and found that CD44high/CD166high subpopulation has significantly greater sphere-forming capacity compared to non-CSC (CD44low/CD166low) counterparts (data not shown).
But his greatest sphere of influence was as an arranger and composer for other jazz artists.
Now get thee inside the great sphere and hark the Hanks heresy.
A 17ft-diameter model of Saturn appears to orbit the great sphere.
Beyond the basic rules of proper use, there is a great sphere of ambiguity.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com