Values closer to the unit score (equal to 1) translate to higher potency, higher predicted bioavailability, or greater pathway perturbation relative to all other chemicals.
Therefore, in order to separate these functional activities and allow greater pathway flexibility, AdhE2 was replaced with a 'TPC7' module in combination with Ahr.
Fine-needle aspiration aspirate tumour biopsies performed on day 7 after treatment showed greater pathway and angiogenesis modulation in the combined treatment that accurately predicted the tumour growth inhibition observed on day 21.
"It's corny, but it's a highway in the sky, a great big pathway: the Milky Way.
"Well, there's the Great Pathway".
Ending conflicts would open the single greatest pathway to global development; the best way to save lives; the best way to foster a generation of children ready, willing and able to sustain development into the future.
Humor is a great pathway to book loving.
This is a great pathway to finding an active rest state.
Similarly, larger contrast sensitivity deficits were found when stimuli were presented dynamically rather than statically, also suggesting greater M-pathway, than P-pathway, impairment (19).
Using the metric of "total" as a measure of overall pathway activity (Table S5), there was greater overall pathway activity for Blast 1 than for Blast 2 in both the basal and FLT3L-potentiated states reflecting significant contributions of both basal and evoked signaling responses.
