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In REG-GB cultures, a serine kinase of the Hpr protein (H16_A0383) and phosphotransferase system (H16_A0384), related to alternate PEP-PTS, were identified, but not expressed at significantly greater levels at 48 h pi with any of the substrates.
In comparison to rCCL21, CCL21-vaults stimulated DC APC activity to greater levels at one tenth the concentration of rCCL21, suggesting a greater DC affinity for the CCL21-vault nanocapsule.
The genes involved in cholesterol biosynthesis that are induced by about two-fold or greater levels at 4 hours are listed.
The genes involved in fatty acid biosynthesis that are induced by about two-fold or greater levels at 4 hours are listed.
In contrast, infected-cell media contained readily measurable IL-6 levels at 24 h p.i. (61.2 ± 1.9 pg/mL) (p < 0.0001 for infected versus mock-infected) and even greater levels at 48 h p.i. (458.8 ± 63.5 pg/mL) (p < 0.00020 for infected versus mock-infected).
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In contrast, relative humidity varied to a greater level at 3 m from the ground, around the upper section of the mask, where the lowest value reached 36% during the day (12 00 to 16:00 hrs) and then peaked at 88% after 20 00 hrs (Table 1).
These proteins accumulated at greater levels than at the centromeres of host chromosomes.
Eros is the great leveller, at least for a moment or two.
In our study cathelicidins were identified at greater levels in M. paratuberculosis infection at 10 months PI in comparison to controls, suggesting a possible role in antimycobacterial activity.
Thus, peritoneal macrophages from PCM mice exhibit significantly greater levels of apoptosis at baseline and when stimulated with pro-apoptotic agents compared with controls.
"The research is clear that failing to take a vacation creates higher levels of stress and greater levels of disengagement at work," Matthews reports.
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