We know both men are capable of memorable work (Underrated Travolta films: The General's Daughter, Primary Colors. Undervalued Williams movies: this year's World's Greatest Dad, Insomnia).
Compared with the typical antipsychotic perphenazine, aripiprazole was associated with a greater frequency of insomnia and dyspepsia, although this was not significant (El-Sayeh & Morganti 2004).
The greater likelihood of insomnia symptoms developing in middle age among women compared to men explained the overall association between gender and psychiatric distress at age 57, but not the extra disadvantages for women in a manual social class.
The adjunctive therapy was also associated with a greater remission from insomnia (50.0%) as compared to control (7.7%) and larger improvement in all diary and actigraphy measures of sleep, except for total sleep time.
HAM-D items with the greatest improvement were insomnia items, feelings of guilt and depressed mood, while in the MADRS, the greatest improvement was seen in reduced sleep, inner tension, reported sadness and suicidal thoughts.
Problems with insomnia were greater for individuals concerned about friends, family and other interpersonal relationships, drug and alcohol use and finances.
The benefit may be greater for those with insomnia comorbidity, probably because good sleep is critical for proper cognition and memory processing.
Among subjects with diabetes, greater sleep fragmentation and insomnia, but not sleep duration, were associated with higher fasting glucose, higher fasting insulin, and higher HOMA even in the fully adjusted models.
