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12 14 18 20 26 In the two studies stratifying by pre-AKI function, AKI with baseline CKD was associated with a substantially greater (fourfold to fivefold) risk of ESKD than AKI in cases without prior CKD 18 20 although notably one study defined CKD at eGFR<45 mL/min/1.73m 20 and the other by a hospital code.
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We found that cytoskeletal disruption had no effect on AQP1 diffusion in the plasma membrane, but that diffusion was increased greater than fourfold in protein de-enriched blebs.
During the complete observation time following CLP (6-48 hrs), aldosterone levels were found to be significantly elevated after CLP-induced sepsis, peaking between 6-24 hrs, where levels were found to be greater than fourfold increased compared with the neg ctrl group (Figure 1C).
The detection of IgG alone is not considered diagnostic unless blood samples are collected 14 days apart and a greater than fourfold increase in levels of specific IgG is detected.
Application of both filters resulted in 450 significant genes with a probability of 97.1% of being differentially expressed equal to or greater than fourfold.
We report here production of transgenic cassava plants expressing zeolin in which storage roots accumulated up to 12.5% dw protein, a greater than fourfold increase compared to controls with no associated accumulation of the protein product in leaf tissues.
However, compared to those untreated controls, a greater than fourfold increase is detected in the histamine-treated samples).
Data from the United States demonstrate a greater than fourfold increase in carcinoma in situ within a 30-year period [ 4].
The presence of renal disease increased from 2% (15 of 740 admissions) in 2000 to 9%6969 of 840 admissions) in 2012, a greater than fourfold increase (p<0.001).
3 There was, however, a greater than fourfold variation in midazolam clearance in the majority of studies in the critically ill.
Any peak not present in at least 80% of all replicates and not enriched to greater than fourfold relative to the GV control was excluded from further analysis.
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