Several philosophers sympathetic to the Rawlsian framework have suggested modifications that would give people with disabilities a greater and more direct role in the social contracting process.
While the precise role of HDAC6 in poly-Q diseases needs to be studied in greater detail, a direct role for HDAC6 in the pathogenesis of AD is suggested by the finding that HDAC6 protein levels are increased in postmortem tissues samples from AD patients (Ding et al, 2008).
From other studies it was reported that the more pronounced effect of the extract in alloxan-induced diabetic mice may possibly be due to the limited or compromised action of insulin in diabetic condition, and conversely a greater and more direct role of the hypoglycemic principle present in the extract [ 40].
Variations in the genic regions, though less frequent, would have a greater possibility of having a direct role in altering the phenotype of an organism [ 52].
Whether this greater autonomic dysfunction has a direct role to play in the generation or persistence of pain in DPN now needs to be the subject of larger prospective studies.
It seems that this was generally due to a greater effect on BMI, although a direct role of BMI in multiple regression analysis was not evident.
No other nation has undergone a greater degree of self-examination about its direct role and complicity in mass murder than it has.
We have shown previously that LFD has significantly greater estrogenic activity than does HFD, eliminating a direct role of diet on HFD-associated mammary tumor phenotypes (La Merrill et al. 2009a).
Ford, suffering from a tire crisis, eroding margins, quality problems and a declining market share, announced that Henry Ford Henry Ford 's great-grandson, William Clay Ford Jr. William Clay Ford Jr., currently the company's chairman, will take a direct role in management.
Sanders said, "Widespread financial criminality on Wall Street played a direct role in causing the world's worst financial crisis since the Great Depression".
One No 10 official said: "The president is asking the UK to play a greater role in training the Afghan national army, as we begin to draw down combat troops and play less of a direct role.
