Sentence examples for greater defects from inspiring English sources

The DCs and macrophages of mice deficient either in TLR2 or TLR9 also showed significantly greater defects in response to IL-12.

Conversely, the CS with biologic mesh group likely had greater defects, and in some cases, bridging with the biologic was undertaken.

As previously published (Dean and Kenny, 2004), a 6 h infection with the effector delivery-defective mutant (espB) did not disrupt Caco-2 barrier function, in contrast to the wild-type strain where a significant loss was first evident 3 h post infection with progressively greater defects over the 6 h infection period (Fig. 2A).

Thrombin mutants with multiple alanine substitution of basic residues showed a progressively greater defect in inhibition potency.

Double mutant (TLR4lps-d/TLR9−/−) mice had an even greater defect in lung bacterial clearance, as compared to single mutant animals (p<0.05), with a 300-fold increase in CFU as compared to infected WT animals.

Furthermore, in Pima Indians, a greater defect in AIR was found in those who subsequently developed type 2 diabetes (7).

This is consistent with the PY1AA mutation exhibiting a greater defect in nuclear localization compared with the PY2AA mutation.

In grade II lesions both US and MR show oedema and fibrillar defects, and grade III lesions show a greater defect associated with haematoma and muscle.

Also, one mutant (L494A, Y496A) showed a greater defect in di-Ub synthesis, perhaps marking the site where Ub binds as a substrate.

Cause set aside, a greater defect in negative selection could allow a threshold to be crossed in which other mechanisms of maintaining tolerance are no longer sufficient to prevent disease.

The greater defect in the DT treated Ebi2-/- CD11c-DTR chimEbi2-/- CD11c-DTRt with a rolEbi2-/- CD11c-DTR supporting Ebi2-/- CD11c-DTRfor the polychimerasntisSRBconsistentell and GC responses.