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Therefore, it is a much greater challenge to develop teaching using a network.
Live attenuated virus vaccines such as cold-adapted influenza (e.g., FluMist®), or oral polio vaccine can provide better mucosal immunity, but these are a greater challenge to develop, and they require an expensive cold chain that complicates delivery in developing countries.
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Therefore, it remains a great challenge to develop alternative cost-effective high-quality luminescent materials and systems with good confidential encryption abilities for high-level information storage and security protection applications.
Considerable recent attention has been paid to homogeneous fluorescent DNA detection with the use of nanostructures as a universal "quencher", but it still remains a great challenge to develop such nanosensor with the benefits of low cost, high speed, sensitivity, and selectivity.
Due to the extremely ultra-low permeability of the reservoirs, it is a great challenge to develop shale reservoir commercially.
Thus, it remains a great challenge to develop feasible methods to prepare hollow nanocrystals with well-defined morphology.
Although many efforts and applications have been achieved for these novel carbon films, it is still a great challenge to develop a novel method to prepare the films at a large scale.
Although many reports have been reported on the rGO sensing devices, it is still a great challenge to develop chemiresistive sensors based on rGO with miniature, low-cost, and portable characteristics.
It is a great challenge to develop DNA barcodes for land plants [ 40, 48].
The presence of multiple copies of genes in amphidiploid rapeseed poses a great challenge to develop allele-specific SNP markers.
It would be a great challenge to develop home-based prevention programs where a task, any task, consistently requires attention 3 times/day.
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