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Over a period of 20 years, and overcoming great technical difficulties, he isolated and characterised the series of elements now known as actinides.
Detailed network data for these are not available because of the great technical difficulties in reliably reconstructing even small networks such as the 302 neuron C. Elegans nervous system [27].
Attempts to assess expression of flaA in the sprout system were met with great technical difficulties due to the tightness of the interactions of the L. monocytogenes cells to the plant tissue and, with RM2992, very few cells present on the plant tissue so that RNA could not be isolated.
However this method suffers from great technical difficulties due to unpredictable dimerization and/or formation of higher aggregates in the two phases, which resulted in erroneously high concentrations (3, 4).
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The issue is made even more serious by the great technical difficulty of the discovery and development of antibacterial compounds.
The physiological response to cold exposure shapes the ability of insects to survive and thrive in these environments, and can be measured, without great technical difficulty, for both basic and applied research.
If only partial necrosis is achieved, future re-treatment may be necessary, which may result in increased patient discomfort, greater technical difficulties, higher failure rates and an increased possibility of complications.
As TV program is a real-time video service, it has greater technical difficulties to overcome than a traditional video file download or online streaming, especially when TV programs are played on handheld devices.
In children however it may be associated with greater technical difficulties and considerable patient fear and anxiety, which may result in distress to the parents and to the staff performing the procedure.
The participants reported less difficulty shaping with a biconical-tipped file and the greatest technical difficulty with a pyramidal-shaped tip.
– Previous spine surgery theoretically exposes the obstetric patient to a greater technical difficulty during regional analgesia for labour or during anaesthesia for caesarean delivery.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com