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No great setback to their cause, you might think.
By and large, this was not any great setback to the bosses.
There is broad agreement that having to wait until traditional criteria are met to harvest organs would constitute a great setback to organ transplantation (even if donation after cardiac death, which invokes traditional criteria, is permitted).
"Polio outbreak in Myanmar after polio free status for over 5 years is a great setback to polio eradication efforts in the region," notes Professor Adik Wibowo, WHO Representative to Myanmar.
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The unwillingness to acknowledge the continuing problem, say many experts, has been the greatest setback to women in achieving salary equity.
In this period of confronting the greatest setback to voting rights in decades, state laws that are attempting to turn back the clock and unfair legislation that creates an environment for the Zimmerman verdict, we must make sure that we remain steadfast in our dedication to justice.
Rush Limbaugh has complained that Mr Bush's legacy may be the greatest increase in domestic spending, and one of the greatest setbacks to liberty, in modern times.
Villani was certain that the Republic of Florence had experienced a great setback on its path to glory with the defeat of the Guelphs by the Ghibellines at the Battle of Montaperti in 1260.
There can be no greater setback than to be cruelly and mercilessly killed.
This has to be a great setback".
That would be a great setback for Mr. Annan, who first proposed the changes, and whose future is increasingly being tied to whatever success he can have with pushing them forward.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com