Sentence examples for great open question from inspiring English sources
That, of course, is a great open question.
Finally, several studies indicate that HPB-CD is unable to cross the blood-brain barrier [6], [28], [29], so the mechanism by which HPB-CD improves the neurological symptoms in NPC1 mice [27] remains a great open question.
To uncover the answers to the greatest open questions about our Universe today, we need to build observatories that are up to the technological challenges that pushing past the current frontiers in astronomy demands.
Whether it would recollapse (with gravity defeating the expansion), expand forever (with the expansion defeating gravity), or live right on the border between the two cases (with expansion and gravity perfectly balanced) was one of cosmology's greatest open questions.
But just how great remains an open question.
Whether all of these elements can be brought together to make great radio remains an open question.
How optimally this suppression can be performed remains an open question of great interest to both the natural science and the control engineering communities.
It is plain-speaking Texas versus self-satisfied Washington, DC; and only an outsider, like Mr Bush, can work with both parties to pass the sort of programmes that have eluded the more partisan Clinton-Gore administration.Yet it is an open question whether greater likeability alone will be enough for Mr Bush to win the election.
Why "directed duties"—as above, those owed to an entity have greater normative priority remains an open question: the only broad consensus is that they do.
To which degree the stroke induced alterations of the immune system that apparently maintain self tolerance but enhance susceptibility to infection might rely on different mechanisms is an open question of greatest clinical relevance.
