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* One great obstacle facing Western ad agencies that want to negotiate deals with Eastern European communications enterprises is uncertainties about how long media executives in those countries will remain in their jobs.
Intrinsic or acquired drug resistance to chemotherapeutic agents represents a great obstacle facing the successful eradication of cancers [1].
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Often the greatest obstacle facing charter schools is finding classroom space.
Perhaps the greatest obstacle facing de Vere's supporters is that he died in 1604, before 10 or so of Shakespeare's plays were written.
Senator Charles E. Schumer announced yesterday that he had formed a blue-ribbon panel to address what he described as the greatest obstacle facing New York City's economy: a lack of office space for the financial services, high technology and biotech industries.
"The current antiquated reassessment system is the single greatest obstacle facing the long term fiscal stability of this county," said Judith A. Jacobs, the Legislature's Democratic presiding officer, as she and her fellow Democrats signed a pledge to overhaul it.
While growing up in India I had seen firsthand the stigma associated with mental illness which is also the greatest obstacle facing the mental health community.
Another example from Mr. Shapiro himself: "Perhaps the greatest obstacle facing de Vere's supporters is that he died in 1604, before 10 or so of Shakespeare's plays were written". Sadly, he didn't list the ten "or so" plays he means.
Access to finance to support farms is perhaps the greatest obstacle faced by smallholders.
Prior to the Digital Age, the greatest obstacle faced by artists trying to make a living, was garnering enough exposure for their work so that it could reach those who appreciated it enough to purchase it.
Probably the greatest obstacle faced by people in the Western world to learning correct, effortless ("classical") singing is the axiom that when you are faced with a problem, "do" something is the usual response!
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com