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That was a great difficulty when I worked in Germany for six years.
Naturally enough, the country finds herself in great difficulty when presented with those who seem keen to resist definition.
You might have thought that writing about famous figures presented no great difficulty when it came to names.
After smaller roles in Paul Thomas Anderson's earlier films, he became a dramatic lead and then a skilled comedian, giving us all great difficulty when trying to define exactly what he is.
Classical methods often face great difficulty when confronted with hard optimization problems present in real situations.
Because of the speckle, a form of multiplicative, locally correlated noise, typical image processing techniques experience a great difficulty when applied to SAR imagery.
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However, as the data keeps getting bigger and bigger, the existing machine learning techniques encounter great difficulties when they are required to handle the unprecedented volume of data.
"Consumers who have been victims of identity theft as a child will face great difficulties when attempting to establish credit later in life," according to information on the Web site of Experian, one of the big three credit-reporting firms.
The lack of standardization of the VOT has led to great difficulties when trying to compare results from different studies.
However, these scales clearly have great difficulties when extended over the range and time course of a degenerative disease.
"My greatest difficulty when I took over was that there was absolutely nothing in the pipeline," she said.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com