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"The great defect of this music," he added, "is that it has to be accompanied by drugs.
Only one point seems to elude Bobbitt, and that is what seems to me to be the great defect of any pre-emptive action by a democratic regime: the electoral rewards for success are slight because the public finds it hard to be grateful for a nonevent.
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To begin with, I realized that my two great defects were the two greatest defects possible: the clumsiness of my writing and my ignorance of the human heart.
Mexico's new leaders have surveyed the PRI's legacy and admit that Mexico and its government have great defects, but they have yet to display the necessary know-how to correct them.
Striving to refashion Shakespeare as a more genteel poet, Alexander Pope, in the preface to his 1725 edition, acknowledged his subject's shortcomings: "It must be own'd that with all these great excellencies he has almost as great defects; and that as he has certainly written better so he has perhaps written worse than any other".
It has two great defects: It undermines the race, and secondly it retards the progress of the country.
And because the majority of white Americans, and white Christians, decided Trump's great defects and dangers were not disqualifiers, he will soon be inaugurated president of the United States.
The book's greatest defect is its failure to answer the question posed by the title.
Or consider what is the Tory brand's greatest defect: the perception that they are the party of the rich.
Thrombin mutants with multiple alanine substitution of basic residues showed a progressively greater defect in inhibition potency.
However, the greatest defect in lung bacterial clearance was observed in TLR4lps-d/TLR9−/− double mutant mice, indicating that both TLR4 and TLR9 are required for optimal clearance.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com