"grave changes" is correct and usable in written English.
You can use it to refer to important changes that could have a serious impact. For example: "The recent events could lead to some grave changes in our country's economic policies."
He writes thoughtful, longer pieces about tech and he often portends grave changes in the industry.
Her photoseries Panta Rhei/Frankfurt is an effort in visual conservation: started in 2009 in reaction to the European Central Bank's decision to relocate to the east end of Frankfurt, and anticipating the grave changes that would soon follow, Fischer intiated her own "photographic documentary" to chronicle the steady demise of some of the city's oldest establishments. .
A grave change associated with human ageing is progressive decline in skeletal muscle mass, a downward spiral that may lead to decreased strength and functionality.
The issue was grave — a change of economic system under a comandante eyeing lifelong rule — but civility prevailed.
Those of us who are technological optimists also see plenty of ways that tech can help enormously with our other grave challenges⎯climate change, cultural misunderstanding, food shortages, inadequate housing, antiquated transportation, and reliance on unsustainable energy sources.
I'm happy just being me!" Lead your procession away from the grave and change from your mourning clothes to your happier attire.
Then he attended a conference on human rights and exhumation, saw the slides of graves and changed his life completely.
Graves allegedly changed his grades more than 90 times during a two-year period, and extended his services to at least five other students.
With respect to grave vascular hypertensive changes, glomerular sclerosis in association with extensive tubulointerstitial scarring (65%), deposits IgA in the mesangium, and typical figures characteristic of FD as were mentioned, it is not possibly to clearly say what was the main cause of the end stage renal disease in this young 26 year-old man.
Differences in the representation of some of these forms in male and female graves may reflect changes in the roles of women and men in community ritual and politics.
In a country where people used to be looked after from cradle to grave, the social change has not only left many Chinese without their traditional support mechanism but also pushed a large number of people into relative poverty.
