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Cells induced with RA for 12 hr and subsequently recultured in liquid culture gradually expressed the differentiated phenotype and lost transferrin receptor expression.
When cultured, these cells gradually expressed ASMA, as well as vimentin, smoothelin and desmin.
When inducer was added, enzyme synthesis resumed, suggesting that the transferred i + gene was becoming gradually expressed and the zygote became phenotypically inducible (fig. 5).
Although ALP is not an osteogenic-specific gene, it is always gradually expressed in the early period of osteogenic differentiation and declined in late period [ 28].
In this study, we demonstrated that the detoxification and metabolism processes are gradually expressed in H. arsenicoxydans to adapt to arsenic-rich environments.
Our interest first focused on the epithelial mucin, MUC4, in this disease because it is not expressed by normal pancreatic tissue but is gradually expressed during pancreatic carcinogenesis from the premalignant lesions, that is, pancreatic intraepithelial neoplasia (PanIN) type 1 (which are MUC4-positive in 17% of the cases) to PDAC (Swartz et al, 2002).
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Circulating erythrocytes for example gradually express PS during aging.
During nearly a year in contact with New York Times reporters, Abu Khadija expressed gradually growing discontent.
Albumin (ALB) and α1-antitrypsin (AAT) transcripts increased gradually, becoming maximally expressed by d20, although levels were still below those of mature hepatocytes.
The study demonstrated that PTTG1 is expressed gradually in primary ductal breast carcinoma, lymph node infiltration, and distant metastases.
Later during cellular differentiation events, the compartments where JMJ is expressed expand gradually, with expression detectable in almost all adult tissues, although the intensities vary among cell types., These observations suggest that histone demethylases link core transcription factor networks to the regulation of chromatin status during cellular differentiation.
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