"The Girl From Paris," which was directed by Christian Carion, is a quiet, slow-moving tale, very much in tune with the gradual rhythms of traditional agricultural life.
For example, the dominant-negative, antimorphic mutation in the Clock gene is responsible for the gradual loss of locomotor rhythms of Clock/Clock mice housed in constant darkness [8] and mania-like behaviors [9].
Leung, L. W. Model of gradual phase shift of theta rhythm in the rat.
Such a hypothesis would mean that the gradual establishment of human circadian rhythms of sleep or temperature results from maturation of the nervous system rather than from conditioning in the strict sense.
Gradual period lengthening of ultradian locomotor rhythms was also observed in Bmal1 −/− animals exposed to amphetamine, a drug similarly targeting DAT (Howell and Kimmel, 2008), but with lower efficacy than Meth (Goodwin et al., 2009).
Nevertheless, it should be considered that arrhythmic control is not completely devoid of rhythm but rather provides a gradual decrease in perceived rhythmicity.
Because Meth leads to increased extracellular DA concentrations as in the case of Slc6a3 gene disruption, we speculated that Meth treatment would result in a, possibly gradual, period lengthening of the ultradian locomotor rhythms.
I told them to be beautiful, to have rhythm and listen to the music". By then, the couple's gradual evolution into dancers was apparent.
But in fact, it comes in many forms, including heart rhythm disturbances that lead to sudden cardiac arrest; heart failure, a gradual weakening of the heart muscle; and angina, a discomfort in the chest due to constricted arteries.
So a lot of fundamental changes but it has to be gradual, you can't just go in and say 'bang' to everything without upsetting rhythm.
The rhythms of control flies were relatively constant across five weeks, although some gradual and subtle reductions in relative peak size and number per day were observed (Figure 5A).
