Sentence examples for gradual regulation from inspiring English sources
Although this variable N-terminal protein extension is not a prerequisite for activity, the catalytic efficiency increases linearly with the number of RLKTQDS heptads, representing a unique mechanism for gradual regulation of enzymatic activity [9], [14].
In the best case, the gradual regulation of ionic and electrophysiological processes in membranes is accompanied by arrhythmias and contractile dysfunction [ 37].
Interestingly, the mRNA level for rplD (ribosomal protein L4) is also reduced during exponential growth, suggesting a gradual regulation of the r-protein transcription units, which already initiates before cells enter stationary phase (see below).
These results suggest that it is the up-regulation of histamine, not achlorhydria nor hypergastrinemia, that contributes to the gradual down-regulation of parietal cell number and gastric atrophy.
With such a design, we were able to identify differentially expressed genes (DEGs) with a gradual up-regulation from normal to pericancerous to cancerous liver, or DEGs with a gradual down-regulation.
Expression analysis by reverse transcription quantitative PCR (RT-qPCR) revealed that increasing temperatures led to a gradual down-regulation of QsMYB1 transcripts with more effect on QsMYB1.1 abundance.
Increased NR2B subunit levels led also to a gradual down-regulation of cerebellar NR2A levels, preceding the development of motor impairment in adult animals.
As shown in Figure 7b, Western blotting analysis showed that the adhesive proteins such as laminin, fibronectin, FAK, and cell cycle protein cyclin D3 exhibited gradual down-regulation expression as the concentration of FMNPs increased.
However, additional examples of gradual up-regulation occur in centroids 10 and 15 (55 additional genes).
This contrasts to the concept of gradual down-regulation in central respiratory sensitivity for carbon dioxide in scleroderma patients [ 4].
In general, the gradual down-regulation of PRH is associated with differentiation of most haematopoietic lineages [ 24, 26].
