Exact(1)
In the case of C3, both pathways show a much more gradual free energy increase, which suggests that the base pairing interaction with a partner guanine (absent for C3) is involved in the steepness of the energy well near the cytosine fully stacked state.
Similar(59)
A state law was passed in 1798 calling for the gradual freeing of slaves by 1828, and many of them settled at Skunk Hollow.
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The gradual disappearance of free music tuition in schools is "disgraceful" - people are no longer being given the opportunity to realise "the sheer joy of music making".
Thanks to a mishmash of outdated but enduring gender roles, the gradual erosion of free time all adults experience, and a dash of misanthropy, I've seen my circle of friends shrink massively over time.
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Even when the cytosines seem to remain stacked, they show a greater range of reversible fluctuations in the direction of the major groove (180° to 270° to 5°) than the minor groove (5° to 90° to 180°), which is consistent with the more gradual increase in free energy in the major groove in the PMF profiles.
But in a broader sense, Mr. Friedman said, much of the world is at a historical turning point, when a gradual acceptance of free-market principles on a philosophical level is beginning to translate into a fundamental movement toward market-oriented policies, institutions and politics.
"Sports fans all over the country are concerned about the gradual decline in free-to-air sport on terrestrial TV". He added: "Children need to see their heroes on television if they're going to be inspired to get involved in sport themselves.
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