Exact(1)
These symptoms might arise from the gradual exacerbation of dyspnea and increase in breathing workload among COPD patients, which in turn engender an augmented intra-abdominal pressure, thus working to further reduce oxygen delivery to splanchnic organs [ 39].
Similar(58)
However, patients with sudden onset exacerbations experienced a significantly shorter recovery time than patients with gradual onset exacerbations (p<0.001), which the investigators considered clinically important.
(2) Gradual tumour growth causes exacerbation of compression neuropathy, creating an indication for surgery.
COPD is a chronic disease with repeated exacerbations resulting in gradual debilitation.
Chronic Obstructive Pulmonary Disease COPDD) is a chronic disease with repeated exacerbations resulting in gradual debilitation.
Furthermore, COPD exacerbations that begin with bacterial symptoms (sputum purulence) are more likely to have sudden, rather than gradual, onset [ 29], suggesting that sudden onset exacerbations may be preferentially preventable with bronchodilators, whereas gradual onset exacerbations may require the addition of corticosteroid therapy.
In general, COPD is characterised by a gradual deterioration in lung function aggravated by exacerbations [ 54].
5 Aaron et al 6 found that COPD exacerbations exhibit two distinct patterns: gradual and sudden onset.
COPD illustrates the 'organ failure' end-of-life trajectory in which a gradual decline is punctuated by acute severe exacerbations, any one of which may be fatal [ 16, 17].
In this form of the disease, onset is usually gradual, and there are alternating intervals of symptom exacerbation and complete symptom remission.
The risk of exacerbation of compression neuropathy caused by gradual tumour growth justifies surgical intervention in symptomatic peripheral nerve tumours.
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