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Literatures have reported that the density changes of dopamine transporter is negatively correlated with the severity degree and grading of disease condition of Parkinson disease (PD).
Objectives: to determine interobserver variation in the measurement of Peak Systolic Velocity (PSV) and grading of disease by means of Duplex scanning (DS) in the popliteal, tibial and pedal arteries.
Grading of disease severity was performed according to a standard protocol.
However, clinical monitoring and choice of therapy largely rely on grading of disease activity.
We anticipate the formation of a study group of interested pathologists to share slides and more formally evaluate this method's acceptability for diagnosis and grading of disease.
This accuracy, it should be stressed, is not in the grading of disease activity, but in the dichotomous determination of disease presence and its anatomic location.
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The treatment and prognosis of patients with head and neck lymphoma depends on the histologic grade of disease and extent of involvement at time of presentation.
The typical histological features of chronic hepatitis and cirrhosis are variable degrees of hepatocellular necrosis and inflammation (activity or grade of disease), fibrosis (stage of disease), and associated fat and iron deposition.
One plausible explanation for the difficulty in mapping susceptibility loci is the existence of considerable heterogeneity in the phenotype of PCa, with significant variation in clinical stage and grade of disease even among family members.
The American College of Rheumatology (ACR) treatment guidelines recommend different strategies for RA patients depending on the time since onset of disease (early vs. established RA), the grade of disease activity (low, moderate or high) and whether the patient is with or without poor prognosis [14].
Linear and logistic (based on >9-point score improvement) regression analysis was used to adjust for potential covariates, including grade of disease, patient age, gender, body mass index, smoking history, medical history (e.g., diabetes or heart disease), use of daily pain medications, fish oil supplementation, knee bracing, and physical therapy.
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