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Assessment of the ability of patients' PBMCs to mediate trastuzumab-mediated ADCC showed a gradient of efficiency according to the FcγRIIIa-158 genotypes, with V/V > V/F > F/F at all time points investigated and a significant difference observed at diagnosis (P = 0.01; Figure 3A).
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Together, our data corroborate and extend the model proposed by Moudgil and Sercarz, which puts forth the gradient of presentation efficiency as a basis for immunodominance [16].
Whether or not this temporal gradient of recombination efficiency is a transgenic issue in the specific line of Nestin-cre mice used in our study, or if the endogenous Nestin promoter also exhibits a similar expression pattern remains to be determined.
To ensure computational efficiency, the shape gradient of the energy conversion efficiency is analytically derived using the material time derivative approach and the adjoint variable method.
In agreement with the chromatin condensation results, a gradient of the DNA repair efficiency was found at different regions along the active genes, with higher repair efficiency in regions close to the transcription start site.
Peak capacity is the primary parameter for evaluation of efficiency in gradient chromatography [ 7].
The effects of these selective parameters are studied on cooled gas efficiency of the first layer of the plant, temperature gradients, electric efficiency, and power of the fuel cell, the electric and CHP efficiencies, and the total electric power of the plant.
A gradient of -3.32 corresponds with 100% PCR efficiency (E = 2).
We propose a matrix-inversion optimization algorithm based on the Biot-Savart law, that using a proper cost function, allows maximizing the uniformity of the gradient and power efficiency.
It is possible that there is a gradient in the efficiency of selection on synonymous sites within the nonrecombining regions.
The Age of Efficiency is over.
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