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The Fallback bargaining and the Borda Scoring algorithms were also selected to prioritize study sub-watersheds based on weighted grades of total score for each variable.
Progression-free survival (PFS) curves by grades of total skin toxicity.
Among KRAS WT patients, there was a significant difference in median PFS by grades of total skin toxicity (grade 3, 7.5 months; grade 2, 6.4 months; grade 1, 3.5 months; grade 0, 1.3 months ; P < 0.001).
When grades of skin toxicity were divided into low grade (grades 0 1) and high grade (grades 2 3), there were significant tendencies that serum levels of AREG, EREG, and HGF were inversely proportional to grades of total skin toxicity (P = 0.021, P = 0.047, and P = 0.019, respectively).
As a novel finding, our study revealed that pretreatment serum levels of particular ligands such as HGF, EREG, and AREG were inversely proportional to the grades of total skin toxicity due to treatment with anti-EGFR antibodies when we divided the grade of skin toxicity into high grade and low grade.
Grades of total skin toxicity were divided into two groups according to the following three patterns: (i) grade 0 and grades 1 3; (ii) grades 0 1 and grades 2 3; and (iii) grade 0 2 and grade 3. Results of AREG, EREG, and HGF are summarized in Table 4.
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The effect on quality of life according to the CAT scores and the mMRC grades of the total subjects was shown in Table 4.
Mean scores of the grading of a total of 10 lobules were calculated for each animal.
The expression of ghrelin and growth hormone secretagogue receptor at mRNA level was detected in adenocarcinomas of the 1st, the 2nd and the 3rd grade of malignancy (total n = 18).
Three cases showed low-grade dysplasia out of total.
The readers graded each of the six articular surfaces of the knee as follows: (1) normal; (2) low-grade cartilage defect (<50%% of total cartilage thickness); (3) high-grade cartilage defect (>50%% of total cartilage thickness).
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