Exact(1)
The similar phenotypes of the mutants raised the possibilities that the causative genetic elements for these mutants were: (1) alleles of the same gene with different grades of expression (Ede and Kelly, 1964b); (2) separate genetic insults within the same pathway; or (3) completely separate defects.
Similar(59)
The STSs which by definition express vimentin are not generally investigated for the prognostic importance of its grade of expression.
Evaluation of A_HSCOREs showed diverse grade of expression of NILCO and targets in ER+, ER- and, TNBC (Table 3).
The grade of expression of the mRNA of APP was even higher in DM than in sIBM.
An overall grade of expression was then assigned by combining both cytoplasmic and nuclear staining results such that only specimens having both high cytoplasmic and nuclear staining scores were graded as high overall staining.
CUL4A-overexpressing tumors had higher grade, absence of expression of PR and BCL2, and a higher percentage of cases expressing EGFR, P-Cadherin, CCNB1, SKP2, and CK5; when compared with tumors that did not overexpress CUL4A (Table 4).
PDE IIIA expression score was calculated from the average of qualified grading of PDE IIIA expression (0 = none, 1 = low, 2 = medium, 3 = high).
The grade of transcript expression was related to the clinical disease activity.
A total of 58 (75.3%) specimens showed any grade of MET expression and 42 (54.5%) were considered as tumours with MET overexpression.
The percentage of pSTAT3 nuclear positive cells were used to classify the grade of its expression as negative (< 5%), weak (6-50%), and strong (51-100%).
Overall, the trends with immunological grading of these expression profiles indicated that the assignment of an immunological relevance to genes could classify patient groups with varied immunological signatures.
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