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The main effectiveness measures of this evaluation would be the total number of cytologies performed, HPV infections detected, lesions of different grades detected, episodes of cancer detected and the number of deaths avoided.
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Retinopathy was taken as any grade detected by direct/indirect ophthalmoscopy and/or ophthalmologist assessment.
The highest SH and PDUS grade detected during the scans was adopted as representative of each joint, respectively.
For instance, the study reporting a good correlation of hypermethylation with stage and grade detected GSTP1 hypermethylation in only 36% of PCa tissues, which is by far the lowest rate reported in the literature.
However, the high grade of the CK-IHC budding grade detected more cases with lymphatic and venous invasion and lymph node metastasis than that of the H&E budding grade (80% vs. 41%, 78% vs. 34%, and 96% vs. 54%, respectively), indicating usefulness of the CK-IHC grade.
Calcifications of various grades were detected in radial artery samples of 30 patients (56%): 11 patients had grade 1, 5 grade 2, 8 grade 3, and 6 grade 4 calcifications.
A higher rate of nausea (all grades) was detected in the cisplatin-containing treatment arms (see Table 4).
Sinusoidal dilation of any grade was detected in 78% samples in the 'bevacizumab group' (43% grade 1 and 35% grade 2), in 67% samples in the 'chemotherapy group' (39% grade 1 and 28% grade 2; P=0.488) and in 48% samples in the 'control group' (only grade 1; treated vs controls P=0.045).
This suggests that approximately 50% of low grade DCIS detected at screening will represent overdiagnosis while overdiagnosis of high grade DCIS would be rare.
The size and metastasis grading were detected.
ER, PgR, HER2, and grade were detected on CNB samples.
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