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Survival in histological subtypes of glioma stratified by tumor grade of samples included in the TCGA dataset.
Overall survival in distinct molecular subtypes of glioma stratified by tumor grade of samples included in the TCGA dataset.
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Interestingly, the most favourable impact on powder respirability was exerted by quick-freezing combined with a certain grade of sample dilution before the pre-freezing step without the use of cryoprotectants.
On the basis of information in these three studies, it is not likely that the discrepancies are attributable to differences in tumour grade of sample sets, whereas patient ethnicity (not given in the publications cited) and details of mutation analysis protocols merit attention in further investigations on the role of KLF6 mutations in prostate cancer.
However, data from a total of 83 additional samples in two other ovarian cancer panels revealed a statistically significant, two-fold elevation of STAMP mRNA in tumors of stages I-III relative to "normal" ovarian tissue (n = 13) (Fig. 2B; see Additional file 2: Table S2 for description and grading of samples plus the raw qPCR data).
The PCR-GGI correctly classified 81 of the 106 non-responders patients in the high grade subgroup of samples (76.5% sensitivity, 95%CI: 67-84%) and 73 of the 164 patients with objective response (OR) or stable disease lasting over six months in the low grade subgroup of samples (44.5% specificity, 95%CI: 37-52%) with an odds ratio of 2.59 (95%CI: 1.51-4.48).
The histologic grade of dysplastic samples was low-grade in nine of 15 (60%) samples and high-grade in six (40%) samples.
The maximum histologic grade of the samples from the esophagectomies ranged from unknown (n = 2) to low-grade/indefinite for dysplasia (1), high-grade dysplasia (8), up through EA (16).
To test for trend of ADAM8 serum levels with rising immunohistologic grade of tumor samples a Jonckheere-Terpstra test was carried out.
According to UICCTNM (1998), the histological grade of the samples was determined to include 26 stage I cases, 14 stage II cases, 30 stage III cases, and 28 stage IV cases.
Splicing patterns of CEACAM1 did not depend on the differentiation grade of tumor sample.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com