Sentence examples for grade of amplification from inspiring English sources

Furthermore, the grade of amplification reflects the expression of the receptor.

A FISH analysis was performed on 7 cases among 11 FGFR2-amplified cases and showed that 6 of these 7 cases were highly amplified, while the remaining 1 had a relatively low grade of amplification.

The FISH analysis revealed that FGFR2 was highly amplified in six of the seven FGFR2-amplified clinical samples (four showed multiple scattered signals and two showed large clustered signals), while the remaining sample exhibited a relatively low grade of amplification (FGFR2/CEN10p=2.2, Figure 2B).

For both clones, not only a intrachromosomal high copy egfr gene amplification can be found which is based upon one abnormal chromosome 7 but also a heterogeneous cell population which differs in the grade of this amplification.

The concentrated virus was brought to a final concentration of 5 mM MgCl2 and incubated with 0.1 U/µL of RNase A (Invitrogen) and 1 U/µL of Amplification Grade DNAse 1 (Invitrogen) for 3 h at room temperature.

Briefly, genomic DNA contamination was minimized by treating 1 μg of total RNA with 1 U of amplification grade DNAse I (Invitrogen, Life Technologies, Carlsbad, CA) according to the manufacturer's protocol.

24 μl of nucleic acid-free water, 3 μl of reaction buffer, 3 μl of Amplification Grade DNase I, and 3 μg of total RNA (1 unit/μl) were added together and centrifuged for 10 seconds to collect the reaction at the bottom of the tube.

In the multivariable model, high nuclear grade and amplification of HER2 were independent factors.

In univariate analyses, several conventional prognostic factors were identified as significant predictive factors for RFS, including tumor stage, nodal stage, histologic grade, and amplification of HER2.

On the basis of the International Neuroblastoma Risk Group INRGG) consensus, seven independent prognostic indices (stage, age, histologic category, grade of tumor differentiation, MYCN amplification status, chromosome 11q status and DNA ploidy) are commonly used for the stratification of patients affected with NTs into defined risk groups.

Conversely, several probes demonstrated substantial rates of amplification in high-grade dysplasia and cancer.