adjusted for age, sex, region of residence, subsite, grade, morphology, deprivation quintile and period.
adjusted for age, sex, region of residence, subsite, stage, grade, morphology, deprivation quintile and period.
To account for missing data on grade, morphology and deprivation quintile, multiple imputation using chained equations (ICE) was employed [ 25, 26].
We used multiple imputation using chained equations (ICEs) to account for missing data on grade, morphology and deprivation quintile (Table 1; Royston, 2005; Nur et al, 2010).
Other variables in the analysis were age, sex, ethnicity, region of residence, primary tumour subsite, stage, grade, morphology, level of deprivation and period of cancer plan implementation.
With univariable and multivariable Cox regression analyses, we assessed influence on overall mortality of age, second primary breast cancer, tumour and nodal stage, grade, morphology, breast surgery, axillary lymph node dissection, chemotherapy, hormonal therapy, targeted therapy, and radiotherapy.
These findings concur with our findings that foveolar GEDs predominantly showed normal/reddish color, flat/depressed shape, and high-grade morphology.
Recent evaluation of oocyte quality is based only on the evaluation of morphology, but this is very limited, and also oocytes with high-grade morphology sometimes do not fertilize or develop into the embryo.
As cellular invasive mucinous carcinomas (with low-grade morphology) clusters in the luminal A molecular subgroup [ 7] and solid papillary carcinoma is considered to mostly represent an intraductal carcinoma with possible associated invasive carcinoma [ 16], these tumors obviously represent low-grade carcinomas with a very good prognosis.
In 2 of the cases with sarcomatoid change, the sarcomatoid areas were in direct continuity with areas showing the stereotypical low-grade morphology (including ISUP nucleolar [nuclear] grade 2 nuclei), indicating true dedifferentiation rather than the existence of a different tumor type.
Similar to CGH studies, distinct expression changes associated with DCIS grade and morphology were found.
