Sentence examples for gr expression patterns from inspiring English sources

The optimized GR IHC assay was used to evaluate GR expression patterns in archival FFPE tissue samples of TNBC (n = 50) obtained from a tumor bank, as well as TNBC samples within a TMA (n = 43; two cores each [1.5 mm]).

It is not known whether GR mRNA and protein abnormalities occur in the OFC in psychotic illness, and to what extent GR expression patterns in the OFC mirror those observed in the DLPFC and/or in other brain regions.

Surprisingly, expression patterns of Gr orthologs between the two honey bee species were distinct.

Expression patterns of Gr orthologs in A. cerana and A. mellifera were determined by relative gene expression analyses.

The next obvious step in studies of these Daphnia Grs will be to determine their expression patterns more precisely.

While in situ hybridization might allow more refined studies of their expression patterns, in D. melanogaster at least, Grs typically are expressed at too low levels for reliable in situ hybridization.

A recent human study investigated developmental changes in GR expression in the dorsolateral PFC from infancy to adulthood and found dynamic patterns of GR isoform expression across the lifespan, suggesting that the neonatal and late adolescent periods represent vulnerability windows to stress during human cortical development [ 191].

In patients, poly-GA, poly-GR, poly-GP and poly-PR showed remarkably similar regional and subcellular expression patterns, suggesting that these proteins are co-translated in most cells and then co-aggregate in p62-positive inclusions [ 38].

Since the discovery of duplicated GRs in a number of teleost fish various studies have investigated the molecular characteristics, tissue expression patterns and functional traits (e.g., hormone binding or transactivation activity sensitivities) of each paralogue in an attempt to explain potential mechanisms by which the two GRs where retained [ 15, 17- 20, 26- 34].

GR expression and binding capacity were assessed by flow cytometry.

However, in earlier studies of GR mRNA, sepsis and septic shock were associated with decreased GR expression.